Due 4/20/19 11p.m EST

Be on time and ORIGINAL WORK!

Don’t ask if you haven’t read directions!

DATA ATTACHED ALONG WITH STEP BY STEP GUIDE!

The Kaplan-Meier curve is a way to evaluate longitudinal data and estimate conditional survival rates through the illustration of a series of conditional probabilities.

For this Assignment, you use the Kaplan-Meier method to evaluate time-to-event data collected through a longitudinal study described in the Week 8 Dataset (SPSS document). You also create a survival curve and estimate survival distributions.

**The Assignment**

Using Wk 8 Dataset (SPSS document)

- D
**ata****Create a variable for Time-to-event by subtracting the start time (variable = start) from the stop time (variable = stop). Label the new variable “Time”.****Produce the appropriate descriptive statistics, numerical and graphical, for the following variables:**

**Event****Interval****Tx****Num****Size****Time**

**Kaplan-Meier Survival Analysis (Without factor or Strata)****Run a Kaplan-Meier analysis in SPSS, using Time as the Time variable and Event as the Status variable (Be sure to define the event). Do not add a factor or strata at this time.****Produce a Survival Table (you do not need to submit this)****Produce a plot of the survival function****What is the mean survival time (include confidence intervals)? What is the median survival time (include confidence intervals)? Why do you think they are so different from each other?**

**Kaplan-Meier Survival Analysis (With Factor)****Run a Kaplan-Meier analysis in SPSS, using Time as the Time variable and Event as the Status variable (Be sure to define the event). Add Tx as the factor.****Test the difference between Tx groups (Compare Factor) using Log-Rank, Breslow, and Tarone-Ware****Produce a plot of the survival function****Describe what the Overall Comparisons mean in terms of treatment groups and survival times.****Kaplan-Meier Survival Analysis (With Strata)****Run a Kaplan-Meier analysis in SPSS, using Time as the Time variable and Event as the Status variable (Be sure to define the event). Add Interval as the Strata variable.****Produce a plot of the survival function for each strata.****Why would you want to produce Kaplan-Meier Survival Curves after stratifying for a variable?**